DxPartner

CDO: Lateral Flow Assay; CLIA; QPCR; Infectious Disease; Cancer Screening; Pregnancy & Fertility Test; Pet/Veterinary Diagnostic

CDMO

IVD Raw Material: Enzymes; Amidite; dNTP; Magnetic Beads

QPCR

Molecular diagnosis refers to the application of molecular biological methods to detect changes in the structure or expression level of genetic material in patients. Molecular diagnosis is the main method of predictive diagnosis, which cannot only diagnose individual genetic diseases, but also prenatal diagnosis. Molecular diagnosis mainly refers to the detection of genes encoding various structural proteins, enzymes, antigens, antibodies and immune active molecules related to diseases.

The main methodologies of molecular diagnosis include QPCR/RT-QPCR, NGS, LAMP, FISH, etc. In particular, QPCR/RT-QPCR is the most important methodology used in molecular diagnosis . With the global spread and outbreak of COVID-19, COVID-19 nucleic acid detection has been widely recognized and accepted worldwide. QPCR/RT-QPCR technology used for detection still has considerable technical barriers and difficulties in the development of in vitro diagnostic reagents.

DxPartner has already owned all the process techniques from new product research and process optimization to large-scale production and manufacturing in its own facility, which can provide high-quality and stable materials and solutions for the specific needs of customers with effectiveness and cost-effectiveness. The following are the relevant biomarkers of QPCR/RT-QPCR platform that can be developed by DxPartner. For more information, pleasecontact us

QPCR/RT-QPCR

◆ Infectious Disease
Group B streptococcal	Respiratory syncytial viruses A/ B	Dengue virus
Epstein-Barr virus	Novel coronavirus 2019-nCoV/influenza A(B) virus	Gonococcus/Chlamydia trachomatis/ureaplasma urealytica
Mycobacterium tuberculosis	Hepatitis C virus	HPV (16/18/52/58/33 type)
Influenza A/B virus	Hepatitis B virus	Enterovirus generic / enterovirus 71 / Coxsackievirus A16
Mycoplasma pneumoniae/Chlamydia pneumoniae

◆ Cancer
ALK gene/ROS1 gene	MGMT gene-methylation	SDC2 gene-methylation
Mutation of the BRAF gene V600E	miR-92a	Septin9 gene-methylation
EGFR/ALK/ROS1 gene-mutant type	MTHFR gene-mutant type	SHOX2/RASSF1A gene-methylation
EML4-ALK fusion gene	NRAS gene-mutant type	TERT gene promoter-mutant type
IDH1 gene-mutant type	PIK3CA gene-mutant type	UGT1A1 gene-polymorphism
JAK2-V617F gene-mutant type	RNF180/Septin9 gene- methylation	Leukemia-associated fusion genes
KRAS/NRAS/PIK3CA/BRAF gene-mutant type	ROS1 gene	MicroRNA
KRAS gene- 8 mutant types

◆ New Born Screening
Herpes simplex virus type I	Measles virus/rubella virus	Aminoglycosides are deafening susceptibility genes
Herpes simplex virus type II	Legionella pneumophila	α- Thalassemia gene-Non- deletion type
Types I and II herpes simplex virus	Methylenetetrahydrofolate reductase gene 677C/T	α- Thalassemia gene-deletion type
Rubella virus	PDS gene mutations	Drug-induced deafness gene-mutant type
Cytomegalovirus	Y chromosome microdeletions	Hereditary deafness gene

◆ Cardiac Disease
CYP2C9 gene mutation	VKORC1 gene-mutant type

◆ Cardiovascular
ALDH2 gene-polymorphism

◆ Digestive disease
Helicobacter pylori

◆ AD
Human APOE gene	Human SLCO1B1 gene

◆ Hypertension
CYP2D6 gene- polymorphism	AGTR1 gene-polymorphism	ACE gene- polymorphism
CYP2C9 gene- polymorphism

◆ Blood lipid
ApoE and SLCO1B1 gene-Polymorphisms

◆ Gynecological disease
Candida albicans

◆ Clinial Microbiology
Salmonella/Shigella bacteria

◆ Therapeutic drugs
HLA-B*15: 02 gene

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